4D Flow MRI Post Processor

Use Case (Flow Pattern)

Features of iTFlow

Track Movement of Vessel

In traditional MRI, only the morphology such as size and the shape of heart ware evaluated, and it is difficult to predict progression of the disease.The software developed by fluid engineering experts, iTFlow is a full-fledged MRI blood flow analysis software that displays the blood flow dynamics of the heart, aorta, pulmonary artery in an easy-to-understand manner, and can track the movement of the blood vessel wall by pulsation.

Energy Loss

Large energy loss becomes a cardiac workload in caortic valve stenosis, and it affects life prognosis in addition.
iTFlow is based on fluid dynamics and circulatory physiology. It can calculates energy loss by computing blood viscosity and flow velocity vector field from MRI flow data.

Wall Shear Stress

If Wall Shear Stress (WSS), which is the force that blood flow rubs against the blood vessel wall, is too strong, blood vessels may be injured and plaque and aneurysm may collapse.
On the contrary, if it is too weak it is know that cholesterol will gradually deposit and plaque will develop.
ITFlow can calculate accurate WSS using its own algorithm and display in color.


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1) Keiichi Itatani Advances in Hemodynamics Research (Nova Science Publisher)
2) Chatzizisis YS, Jonas M, et al.  Prediction of the localization of high-risk coronary atherosclerotic plaques on the basis of low endothelial shear stress: an intravascular ultrasound and histopathology natural history study. Circulation. 2008;117(8)993-1002.
3) Nabeta T, et al. Vortex flow energy loss reflects therapeutic effect in dilated cardiomyopathy. Eur Heart J.

This software is only for researches. It cannot be applied to clinical situations.