This study was conducted by Dr. Takei and colleagues from the Graduate School of Dokkyo Medical University.
Using 4D Flow MRI, they investigated the flow dynamics within the false lumen of patients who had undergone the frozen elephant trunk (FET) procedure. Their aim was to identify hemodynamic predictors of false lumen expansion and adverse false lumen remodeling.

The study concluded that blood flow in the false lumen after FET surgery exhibits a biphasic pattern during systole. Furthermore, the range between peak and minimum flow velocities may play a key role as a hemodynamic predictor of false lumen expansion rate and adverse remodeling. While further research is needed to validate these findings, the results hold promise for clinical application—particularly in identifying FET patients who may require additional surgical intervention, alongside other morphological predictive factors.

Yusuke Takei, Shohei Miyazaki, Kohei Suzuki, Shunsuke Saito, Hayato Oogaki, Yuki Muraoka, Takeshi Ogasawara, Masahiro Tezuka, Ikuko Shibasaki & Hirotsugu Fukuda , "Hemodynamic predictors of negative false lumen remodeling after frozen elephant trunk for acute aortic dissection", SPRINGER NATURE LINK, Volume 72, pages 376–386, (2024) (2023) https://doi.org/10.1007/s11748-023-01984-x.