Reduction in thrombogenic activity and thrombocytopenia after transcatheter aortic valve implantation — The ATTRACTIVE-TTAS study
Bleeding complications after transcatheter aortic valve implantation (TAVI) is a major problem in clinical practice. However, there is few information on thrombogenicity after TAVI.
The aim of this study was to establish a monitoring of total thrombogenicity in perioperative TAVI using the Total Thrombus-formation Analysis System (T-TAS) under flow condition.
The show that Although high-molecular-weight von Willebrand factor(HMW-vWF) multimers improved earlier after TAVI, total thrombogenic activity evaluated by T-TAS remained relatively low followed by improvement in thrombogenic activity at 30 days after TAVI.
Masanobu Ishii,Koichi Kaikita,Tatsuro Mitsuse.Nobuhiro Nakanishi.Yu Oimatsu,Takayoshi Yamashita,Suguru Nagamatsu,Noriaki Tabata,Koichiro Fujisue,Daisuke Sueta,Seiji Takashio,Yuichiro Arima,Kenji Sakamoto,Eiichiro Yamamoto,Kenichi Tsujita, "Reduction in thrombogenic activity and thrombocytopenia after transcatheter aortic valve implantation — The ATTRACTIVE-TTAS study", IJC Heart & Vasculature, Published Online (2019) .
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