Diastolic dysfunction is an early clinical feature of feline hypertrophic cardiomyopathy (HCM).
The study objectives were to evaluate color Doppler M-mode derived IVPG calculation in cats as a non-invasive assessment of the left ventricular relaxation property, to determine the normal ranges of peak IVPG in cats and investigate the influence of left ventricular function and heart rate (HR).
The show that Feline IVPGs increases with HR and a short IVRT(isovolumic relaxation time), which was believed to be a normal physiologic adrenergic response associated with an increased sympathetic tone. Future studies of segmental IVPG changes in feline HCM are needed to evaluate the clinical applicability of color Doppler M-mode estimated IVPGs in feline cardiology.

Katsuo Matsuura,Maiken B.T.BachDVM,Ken Takahashi,Jakob L.Willesen,Jørgen Koch,Ryou Tanaka, "Non-invasive assessment of left ventricular relaxation property using color M-mode-derived intraventricular pressure gradients in cats", Journal of Veterinary Cardiology, (2022) https://doi.org/10.1016/j.jvc.2022.03.006.