Low Wall Shear Stress Is Associated with Saphenous Vein Graft Stenosis in Patients with Coronary Artery Bypass Grafting
Biomechanical forces may play a key role in saphenous vein graft (SVG) disease after coronary artery bypass graft (CABG) surgery.
The primary goal of this study was to investigate the association between abnormal shear stresses and SVG failure using patient-specific and multi-scale CFD methods.
The show that they found a significant difference in
normalized WSS in local SVG regions that developed stenosis compared to control segments.
They found no significant difference in whole SVG hemodynamic and anatomic parameters.
Muhammad Owais Khan, Justin S. Tran, Han Zhu, Jack Boyd, René R. Sevag Packard, Ronald P. Karlsberg, Andrew M. Kahn & Alison L. Marsden , "Low Wall Shear Stress Is Associated with Saphenous Vein Graft Stenosis in Patients with Coronary Artery Bypass Grafting", Journal of Cardiovascular Translational Research, 14 (2021) 770–781.
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