The bicuspid aortic valve (BAV) is a major risk factor for the progression of aortic dilation (AD) because of the induced abnormal blood flow environment in aorta.
The differences in the development of AD induced by BAV phenotypes remains unclear.
The objective of this study was to assess the potential locations of AD induced by different phenotypes of BAV.
The show that the BAV morphotype affects the aortic hemodynamics, and the abnormal blood flow associated with BAV may play a role in AD.

Qianwen Hou,Keyi Tao,Tianming Du,Hongge Wei,Honghui Zhang,Shiliang Chen,Youlian Pan,Aike Qiao, "A computational analysis of potential aortic dilation induced by the hemodynamic effects of bicuspid aortic valve phenotypes", Computer Methods and Programs in Biomedicine, (2022) https://doi.org/10.1016/j.cmpb.2022.106811.