There is no subjective, definitive evaluation method for therapeutic indication other than presenting symptoms in aortic regurgitation (AR).
The purpose of the present study was to evaluate whether energy loss in patients with chronic aortic regurgitation can quantify their subjective symptoms more clearly than other conventional metrics.
The show that EL calculated by VFM can quantify patients' subjective symptoms more accurately than other conventional metrics in chronic AR.

Atsushi Kainuma, Keiichi Itatani, Koichi Akiyama, Yoshifumi Naito, Maki Ishii, Masaru Shimizu, Junya Ohara, Naotoshi Nakamura, Yasufumi Nakajima, Satoshi Numata, Hitoshi Yaku and Teiji Sawa, "Preoperative Left Ventricular Energy Loss in the Operating Theater Reflects Subjective Symptoms in Chronic Aortic Regurgitation", Frontiers in surgery, Published Online (2022) https://doi.org/10.3389/fsurg.2022.739743.