The global effect of chronic pulmonary regurgitation (PR) on right ventricular (RV) dilation and dysfunction in repaired Tetralogy of Fallot (rTOF) patients is well studied by cardiovascular magnetic resonance (CMR).
However, the links between PR in the RV outflow tract (RVOT), RV dysfunction and exercise intolerance are not clarified by conventional measurements.
In their study, we quantified regional vorticity and energy loss in rTOF patients and correlated these parameters with RV dysfunction and exercise capacity.
The show that in rTOF patients, vorticity and energy loss dominate the RVOT compared to tricuspid inflow, correlating with RV dysfunction and exercise intolerance.

Yue-Hin Loke, Francesco Capuano, Vincent Cleveland, Jason G. Mandell, Elias Balaras & Laura J. Olivieri , "Moving beyond size: vorticity and energy loss are correlated with right ventricular dysfunction and exercise intolerance in repaired Tetralogy of Fallot", Journal of Cardiovascular Magnetic Resonance , Published Online (2021) https://doi.org/10.1186/s12968-021-00789-2.