Aging increases cardiovascular stiffness and structural changes due to cardiomyopathy, hypertension, ischemia, or valvular diseases, resulting in left ventricular (LV) diastolic dysfunction.
The study investigated EL(Energy Loss) in LV( Left Ventricle) among hypertensive elderly patients and examined factors contributing to EL.
The result that Among elderly patients with hypertension, peak EL in the LV was
higher during ED( Early-Diastolic) and LD(Late-Diastolic) than during Sys(systolic), and peak EL in the left ventricle during the late-diastolic and systolic phases was affected by systolic blood flow in LVOT(Left Ventricular
Outflow Tract) and LV transmitral flow.

Shutaro Futami MD,Joji Ishikawa MD, PhD,Teppei Maeda,Masuyo Kawano,Chieko Sakurayama,Kazumasa Harada MD, PhD, "Factors contributing to energy loss in left ventricle during diastolic and systolic phases in elderly patients", Echocardiography, (2021) https://doi.org/10.1111/echo.14930.