Systemic lupus erythematosus (SLE) is a chronic autoimmune
inflammatory disease that affects various connective tissues
and is much more common in females than males.
In this study, compare the intraventricular hemodynamics of 60 females with systemic lupus erythematosus (SLE) and 61 healthy
female controls, and determine cardiac function changes using vector flow mapping (VFM).
The result that they used VFM to identify impaired blood flow efficiency in
SLE patients during diastole and certain systole phases based
on measurements of the vortex and EL.

Yingying Wang & Jian Hong & Rongbin Yu & Di Xu, "Evaluation of left ventricular function by vector flow mapping in females with systemic lupus erythematosus", Clinical Rheumatology, (2021) https://doi.org/10.1007/s10067-021-05747-y.