This study aimed to investigate the correlation between aortic valve protein levels and vector flow mapping of wall shear stress and oscillatory shear index in patients supported with continuous-flow left ventricular assist devices (CF-LVADs). The results showed a significant correlation between aortic valve protein levels and hemodynamic parameters, suggesting that CF-LVAD support may affect aortic valve function through changes in wall shear stress and oscillatory shear index. These findings could have important implications for patient management and device development.

Serge Kobsa, MD, PhD Koichi Akiyama, MD, PhD Samantha K. Nemeth, MA, MPH Paul A. Kurlansky, MD Yoshifumi Naka, MD, PhD Koji Takeda, MD, PhD Keiichi Itatani, MD, PhD Emily G. Werth, PhD Lewis M. Brown, PhD Giovanni Ferrari, PhD Hiroo Takayama, MD, PhD , "Correlation between aortic valve protein levels and vector flow mapping of wall shear stress and oscillatory shear index in patients supported with continuous-flow left ventricular assist devices", Journal of Heart and Lung Transplantation, Volume 42, Issue 1 (2022) 10.1016/j.healun.2022.09.0.