Case Review

Alcohol septal ablation markedly reduces energy loss in hypertrophic cardiomyopathy with left ventricular outflow tract obstruction: A four-dimensional flow cardiac magnetic resonance study
Alcohol septal ablation (ASA), a transcatheter procedure, is an alternative to septal myectomy, that is indicated in patients with high surgery risk due to serious comorbidities or advanced age.
This study aimed to investigate the influence of ASA on energy loss in the left ventricle (LV) and aortic root as measured by 4D flow MRI in HCM(hypertrophic cardiomyopathy) patients with LVOTO(left ventricular outflow tract obstruction).
The show that ASA in HCM patients with LVOTO significantly reduced energy loss within the LV and aortic root as quantified by 4D flow MRI, indicating a substantial decrease in the cardiac workload.
Reference
Zhehao Dai,Nobuo Iguchi,Itaru Takamisawa,Morimasa Takayama,Mamoru Nanasato,Mitsuru Kanisawa,Naokazu Mizuno,Shohei Miyazaki,Mitsuaki Isobe, "Alcohol septal ablation markedly reduces energy loss in hypertrophic cardiomyopathy with left ventricular outflow tract obstruction: A four-dimensional flow cardiac magnetic resonance study", IJC Heart & Vasculature, 37 (2021) https://doi.org/10.1016/j.ijcha.2021.100886.
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